How does pulmonary embolism cause pulmonary hypertension?

[Knicks]

Trying to reason it out, but I'm drawing a blank. =/

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[Charles_Carmichael]

Isn't it just that blockage of a pulmonary artery causes an increased pressure behind it (since blood is being backed-up and not flowing through)?

 

[dienekes88]

Trying to reason it out, but I'm drawing a blank. =/

Are you talking about an acute increase in pulmonary vascular resistance or chronic thromboembolic pulmonary hypertension (WHO group 4 Pulmonary Hypertension).

In the former, it's both obstruction and reactive pulmonary vasoconstriction (hypoxia, platelet/inflammatory mediators). That leads to an increase in PVR, which requires higher pressures to move the same CO over the pulmonary vascular bed.

 

[jdh71]

Trying to reason it out, but I'm drawing a blank. =/

What type are you talking about acute or dana point type 4?

 

[jdh71]

Are you talking about an acute increase in pulmonary vascular resistance or chronic thromboembolic pulmonary hypertension (WHO group 4 Pulmonary Hypertension).

In the former, it's both obstruction and reactive pulmonary vasoconstriction (hypoxia, platelet/inflammatory mediators). That leads to an increase in PVR, which requires higher pressures to move the same CO over the pulmonary vascular bed.

beat me to it

should read the whole thread first