This would be my suggestion concerning how much and what you should read to get an Honors... (this is provided that you have a reasonable patient load and are doing a rotation that will encourage student participation):
1. You should know your patient's chart better than anyone else on your team. You don't have to have it memorized down to the date for each surgery (unless you are on Surgery and they are very demanding), and you don't have to be able to rattle off the patient's entire medical history off the top of your head. However, you are the "expert" historian when it comes to that patient... you shouldn't be "surprised" by factoids that the interns, residents, or attendings bring up, and you should be able to quickly remind them of necessary information.
2. You need to read whatever necessary to have a sound understanding of the patient's disease process. Although no one would expect you to have a complete understanding of Pneumocystis carinii pneumonia in your AIDS patient the second he/she presents (though they may throw out a few questions just to see what your basic knowledge is), they will certainly expect you to be able to answer questions on follow-up days. You should try to review a little bit of general medicine every day (i.e. medicine recall, blueprints, palm resources, whatever), and then make sure that you read about a patient's specific condition as soon as possible (certainly by the next day).
3. Journal articles, case reports, and EBM should also be incorporated. This is not to say that you have every piece of literature in your hand right after you see the patient, but while you are researching the patient's condition after he/she has presented, you should concurrently bring up 1-2 pertinent studies, articles, etc. Although Up-To-Date is wonderful for a general reference, these articles should be the original studies/case reports that were drawn upon by Up-To-Date (i.e. don't rely on Up-To-Date to be your only journal reference).
4. Read the news (or at least glance at the Yahoo!, Google, MSN, etc. version). It is also important to have at least a basic knowledge of any major topics in medicine/health, politics, or other breaking stories. A truly exceptional student is not only able to take care of patients and be a walking encylcopedia of medical knowledge, but they also need to have some understanding of the world around them. Also, this is a great way to impress your attendings with your political savvy (even if they don't agree with you, they will appreciate your ability to add to discussions.) I don't know how the rest of you feel, but it seemed as if these topics were brought up almost just as often as patient care, and it couldn't hurt to have some knowledge to add to these conversations as well...
This may seem like quite an impressive list, but I really think it's manageable if you just force yourself to stay on top of things and selectively read what seems important. I don't think anyone would expect you to be a world's expert during rounds, but it is important to be able to hold your own and have at least demonstrated that you know how to find these different sources of information.
Good Luck!
😀