I think it depends on your interests. If you want Beyonce/Taylor Swift to be coming to your city, it's not going to be likely in a 500k pop city. When you travel to a city and google "things to do in xyz" there is a marked difference between places depending on size. Festivals, pop ups, night life, restaurants, theater/orchestra/ballet, etc do almost precisely vary by the population of the city/metro.
While I personal think there are a ton of great cities that are not coastal in this country, there is certainly a buzz to being in the big heavy hitting metros in the US. Docs make enough money to choose a thing or two (e.g. have a ferrari, nice boat, vacation house, live in a HCoL area, retire early) but not enough money to do everything. People need to pick and choose what matters to them. Or partner with another high income earner if you really want it all 😆.