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- Oct 26, 2017
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I'm looking for textbooks or papers that could provide a "state of the art" overview with regard to pathophysiology for major psychiatric illnesses. Obviously there are a lot of question marks here. I'm looking for information that is current and summarizes/synthesizes recent findings.
Most papers go into fine detail without clear organization as to which elements are more empirically understood than others. In schizophrenia, for instance, papers will discuss the interactions between sub-regions of the hypothalamus, midbrain, and cortical areas and go onto describe how multiple neurotransmitter systems and endogenous neurosteroids might affect them. I don't know if it's just me, but I find that stuff unreadable. I've always enjoyed neurobiology but without an organized foundational description, it's hard to stay abreast of developments.
The closest thing I've come to (and probably what I've relied upon throughout training), is Stahl's descriptions of mental illnesses in his pharmacology text. Despite it's flaws, it did serve as a good introduction to DA theories of schizophrenia and laying out the theory about interneurons, glutamate, and NDMA receptors.
Most papers go into fine detail without clear organization as to which elements are more empirically understood than others. In schizophrenia, for instance, papers will discuss the interactions between sub-regions of the hypothalamus, midbrain, and cortical areas and go onto describe how multiple neurotransmitter systems and endogenous neurosteroids might affect them. I don't know if it's just me, but I find that stuff unreadable. I've always enjoyed neurobiology but without an organized foundational description, it's hard to stay abreast of developments.
The closest thing I've come to (and probably what I've relied upon throughout training), is Stahl's descriptions of mental illnesses in his pharmacology text. Despite it's flaws, it did serve as a good introduction to DA theories of schizophrenia and laying out the theory about interneurons, glutamate, and NDMA receptors.
