How to updated submitted programs with new LOR?

[Marrowist]

Do I simply hit the "Submit Changes" button?

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[DrMikeP]

Do I simply hit the "Submit Changes" button?

Yes, but some schools don't update their apps unless you email them to let them know. Some may want the new LOR's emailed to them directly by the submitter. So best to contact the med schools and ask what they want or risk missing out on some.