Higher specifid gravity compared to CSF. When injected intrathecally will want to go down to dependent areas. Hyperbaric mixutre achieved with a dextrose solution (8.25% Dextose where I train). Positioning is key. One must recall the highest and lowest points of the intrathecal space when in different positions.
Hypobaric usually acheived w/ sterile water. Lower specific gravity than CSF. Will want to float up to non dependent areas.
translation: does it sink or float relative to CSF. ie, if you put in a hypodense solution and put the pt in trendelenberg, you get the solution in the lumbar area. that's the general idea.