Hyperparathyroidism & cAMP

[vsmedic]

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Got a quick question..

In Hyperparathyroidsim, why is there an increase in urinary cAMP?

 

[SomeDoc]

Got a quick question..

In Hyperparathyroidsim, why is there an increase in urinary cAMP?

PTH works via the Gs G-protein coupled receptor system, which leads to increased cAMP.

Source: a well known Q-bank.

 

[vsmedic]

Thanks, Somedoc. Gooduck

 

[eduro25]

SomeDoc is right vsmedic , as receptors are stimulated, second msn AMPc is released. Just to add more info, thats the same reason why you get low urinary AMPc in PseudoHypoparathyroidism (resistance to PTH action in receptors)

Regards,

 

[vsmedic]

Thanks guys.

Do you know where i can find a pic/ list of all receptors acting in their different mechanisms?

 

[FreakofMeds]

Thanks guys.

Do you know where i can find a pic/ list of all receptors acting in their different mechanisms?

There is a good list in the endocrine section of First Aid Step 1, listing the mechanism of most hormones. There is also a similar list for receptor mechanisms of neurotransmitters in the Pharma section of First Aid Step 1.