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Colds are caused by viruses, so why is it that people think that if you're cold, like if you go out of the house without a coat on and it's 20 degrees, you'll catch a cold?
Two reasons back that up that "ol'wise tale":
1) In cold weather there increased aersol transmission of orthomyxovirsues via aerosols:
http://www.ncbi.nlm.nih.gov/pubmed/18367530
2) Cold likely causes physiological stress (increasing cortisol, vasoconstricting, etc) which weakens the immune system and making you more susceptible to infection:
http://www.ncbi.nlm.nih.gov/pubmed/17705968
Because "transmission" is enhanced during winter months, staying warm, makes sure your immune system isn't "stressed" and you are not susceptible these infections that more easily spread.
P.S. Often, those "wise tales" are more right than we think... we just don't understand why, haha.
cold -> people stay indoors -> viruses gets passed around
viruses take a couple of days to incubate and start destroying to upper airway -> symptoms. it's more coincidental, infection probably took place a couple of days before it got really really cold, when everyone started to stay indoors more
Also I think lymphocytes work better at higher temperatures, hence one of the many reasons why you get a fever..
Just to add to what you are saying above: during the cold season, the virus spreads more because more people would stay indoor than outdoor...However, during the spring/summer, less people congregate indoor than outdoor (well, it is hot and humid inside, who would want to stay indoor)...So, if you have 1 pg of viruses, the incidence rate would be much higher during the winter season for the aforementioned reason than summer....
You could mitigate the transmission rate by constantly washing your hands and avoid people sneezing in your face since as people have said in this thread, the cold virus or rhinovirus is spread by aerosol!
I am not so sure about this. If this was true (just being indoors), you would not see "seasonal" flux of orthomyxovirus infections and rhinovirus infections in the winter in "old people homes" (it would just be constantly high). They always have a higher incidence, but it is especially high (spike) in the winter. Yet, they are indoors most of the day and most of the year.
I think it's more simple than that. I think when you don't wear a jacket or whatever, you have to expend more basal energy keeping your core temperature up, leaving less energy to spend on the function of your immune system. The result is a transient immuno suppression which allows already colonized pathogens (viruses) to start to grow out of control or get a head start on your immune system.
Obviously the cold air also paralyzes the mucociliary escalator, which doesn't help, but that happens even if you have a coat on.
I can't back any of this up, that is my theory.
Interesting, but the inverse should have also been true to consider valid IMO..that is...during summer time or Sub-Saharan desert residents should have been prone to infection because the body would invest so much energy to cool itself off. Thus, "The result is a transient immuno suppression which allows already colonized pathogens (viruses) to start to grow out of control or get a head start on your immune system."
NO?
Ahhhh never thought of that good call. You are very astute.
My response to that (just to keep the conversation alive) would be that if you were overheated to the point where you felt like crap (like play soccer all day with a heat index over 100 degrees) you probably would have a higher chance of getting sick in the ensuing days as well. But I would explain that with a different self made-up mechanism:
Core temperature reaches like 100 degrees, cellular enzymatic processes become backlogged from non-ideal temperatures, heat shock proteins are expressed, total body cellular efficiency drops==> better chance of getting sick.
I gave this question a thought when I was student myself. It's quite interesting.
I have been taught that there is no strong evidence which shows that exposure to low temperatures causes a common cold, but more recently I have read that this is not necessarily the case. Here are my thoughts on this (can't be bothered to find the research on pubmed):
1. Constriction of arteries to the nose due to lower temperature reduces the efficiency of the immune defence in the nose. This eases entry of vira into the blood through the nose.
2. A universal weakening of the immune defence in the body (as others here have pointed out)
3. Staying inside in cold temperatures (partly explains the high prevalence of cold during the winter, but not why going out in the cold causes a cold - perhaps it's a co-incidence?)
4. Lower levels of D-vitamin during the winter period due to less sun exposure causes weaking of the immune system (fx. Th17 cells).
I personally believe that going out in the cold without a jacket INCREASES THE RISK of a common cold, but other factors (vira) are also required.