General I want to be a physician scientist

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Goro

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Hello,

I would like some advice and what I can do to increase my chances of getting an M.D. Ph.D.

Background:
I went to a community college for two years and graduated with a 3.51 GPA. I am now a junior at a state university pursuing a BS in Biomedical Engineering. At university, my GPA is a 3.35 which is peculiar since that means my GPA didn't transfer over from cc. When I calculate my science GPA it is around 3.35. For a semester at cc, a tutored a group of students in a psychology course. I have one year of doing botanical research from my community college. (research I wasn't passionate about but at the time it was the only opportunity for me to gain experience). I also have one year of doing research at a university hospital on cancer biology. (Which I'm still doing now because I like it a lot). With this cancer biology lab work, I do basic pipetting, western blots and protein assays but I have also mentored new research associates and have presented lab findings at two learning institutions. I currently have no publications under my name would like to get more research experience (preferably paid) to broaden my horizons. I have applied to summer research programs and I got accepted into one at U of Buffalo but I declined it because I want to finish my pre-reqs to start studying for the MCAT. I still have two more years of college (I'm doing year more after senior year) to finish my bachelor's.

My goal is to do more research and at my institution and find some clinical experience as well (I'm still interested in patient care). My goal beyond undergrad is to go to a Postbaccalaureate Research Education Program or Master's program so I conduct more research to become a competitive MSTP applicant. My passion leans toward research as you can tell but I still long to do work with patients and have clinical training.

What is your recommended course of action for me? Or what advice do you have for me? Feel free to be blunt with me.
You can do plenty of research as an MD.

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You can do plenty of research as an MD.

Yes, but there's a reason you exist, right? There are very few strict MD PI's nowadays and none among the young, without PhD support as a CoI or Co-PI, the Investigator part of any grant application is getting a 5 or higher if they are young nowadays for lack of qualified personnel!

To the OP, you will need to communicate your research expertise better than this as the way that I read your background is more a technical than a scientific one. There are a couple of warning signs based on what you wrote, and I am going to reveal them to you because they are known pitfalls in graduate applications:

1. NEVER speak or write a research statement that is not outcome related especially if it is personal related (the term is researcher narcissism) - When discussing a research background to a professional and not lay audience, it should be guided by the direct work rather than the tools (always discuss the problem before tools).

Contrast:

A. Last year, I used a combination of C++, Assembly, and XML to develop a common data model for inpatient medication dispensing and administration. I used the Assembly to write the medication administration record ties to the medication dispensing equipment, XML to pass messages from the providers to pharmacy and from pharmacy to the frontline, and C++ as the framework for this solution to execute. I supervised a team of twenty staff to implement these protocols and presented on those trials at two national conferences.

B. There are three perspectives on inpatient medications that do not necessarily reconcile: the provider (usually physician) who orders the medications, the pharmacist or frontline med administrator who fills it, and the frontline med administrator who administers the med to the patient at the bedside. Reconciliation issues are troublesome, whether an order gets to the pharmacy can be an issue or an inventory discrepancy between pharmacy and the frontline may mean theft, or that the frontline does not follow the provider's intentions and judgments occur. I spent last year working on a common data model that tracks this process from ordering to administration and with tracing information for when one of those three perspectives are subverted, because a unified model of medication inpatient administration allows for process intervention in all aspects of the med use process.

Statement A is management, but also, focuses on the tools and me rather than the problem. There is no context given to the problem, and I sound like a technician. Statement B is the one that I give to normal professionals who are not specialists in the field (I have a specific jargon-heavy but extremely precise elevator talk for my real peers and those who fund my work when I do wear the research hat).

2. Always speak or write in forward looking statements as you should be a walking, talking advertisement about your work rather than about you. This is the way I talk about my research time to my peers.

C.
There are at least three perspectives on inpatient medications that do not necessarily reconcile: the provider (usually physician) who orders the medications, the pharmacist or frontline med administrator who fills it, and the frontline med administrator who administers the med to the patient at the bedside. We are working on a generalizable common data model, and we have a version that tracks the process from intention to execution right now. What we are discovering are all the ways that the process gets subverted (frontline takes immediate action with a STAT dose, pharmacy stocks out of a drug and does an in-place change, providers change their mind and cancel or reroute orders). Alongside testing the normal scenarios that should occur from provider to pharmacy to patient, we are extending the model to account for exceptions and in-practice process subversions which extends the generalizability of the model beyond a research flat file into an operations process flow adaptable to multiple components such as cursory data analysis (one who just needs a list of the inpatient meds) and process analysis (for the exceptions to a particular arm of practice such as a focus on ordering or a focus on conversions).

The best research statements talk about a past problem, a present working solution, and a future potential for an even better solution.

Now, revise what you wrote for your research statement in light of that. If you cannot, then that is what your problem is for a research statement, but if you cannot make one work, you cannot admit for PhD work. The book I usually recommend to prospective graduate students is Getting What You Came For by Peters. It's old, but the advice is still very sound.
 
I think you make a great point. If I'm not getting research positions I want maybe I need to improve how I tell the admission committees about the research I do.

Tell me how does this sound?

"Neuroblastoma is a pediatric cancer of the sympathetic nervous and high-risk patients do not respond well to treatment whether it is chemotherapy, radiotherapy, etc. Many researchers have noticed that neuroblastoma cells have a dependency on glucose for energy. In our investigation, we look for a way to disrupt glycolysis by using ketone bodies. These ketone bodies are created in the liver when the body lacks intake of glucose and compensates by using fatty acids to form ATP. This process can occur when people are fasting or are in a glucose-restrictive diet. In addition, ketone bodies have been known to have anti-tumor properties. Since one of the side effects of chemotherapy is lack of appetite then it is better to use these ketone bodies as a complementary supplement in combination with conventional neuroblastoma therapy."
That's better, but what are you doing for the research? What you wrote is just a factual statement, not actual work.
 
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