If ATP can be produced in the absence of oxygen through fermentation, then why do people...

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unsavedhero

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... die from a lack of oxygen? I know that fermentation produces significantly less ATP (2atp) than the electron transport chain (34) does, so is that why we can die from a lack of oxygen? Because fermentation is too inefficient of a process?
 
I mean, it's been a long time for me, but...yes? That, and something about acidosis. Don't think the body likes hanging out at a pH of 6.5 too much.
 
I mean, it's been a long time for me, but...yes? That, and something about acidosis. Don't think the body likes hanging out at a pH of 6.5 too much.
good point. completely forgot about the lactic acid lol. thanks. studying for tomorrows bio 2 exam and i just got curious lol
 
... die from a lack of oxygen? I know that fermentation produces significantly less ATP (2atp) than the electron transport chain (34) does, so is that why we can die from a lack of oxygen? Because fermentation is too inefficient of a process?
Brain metabolism requires a lot more than 2 atp per GLC molecule burned off.
 
Glycolysis alone is not enough to fuel most cells.

Remember that fermentation is just way to regenerate NAD+. Fermentation does not make ATP.

Good luck on your exam tomorrow.
oh right fermentation does not produce atp but the glycolysis that leads up to the fermentation has a net yield of 2 atp. thanks 🙂
 
OP try this. Milk is basic so breathe milk in through your nose and hold your breath as long as possible. You will be amazed.
 
Fermentation is a way to reduce pyruvate into lactic acid, releasing NAD+ to keep glycolysis going. You get an oxygen debt and are then forced to breathe heavily to oxidize the lactic acid back into pyruvate, which can move on to the mitochondria (where O2 goes). You are still breathing.

If you are being suffocated or have no O2, your brain starts dying and you can't do glycolysis or anything for that matter. Your brain controls it all.
 
It's been a while for me as well, but I believe the lack of NAD+ causes red blood cells to prematurely die due to inability to protect themselves from reactive oxygen species. This leads to anemia, and therefore, hypoxemia which worsens hypoxia and metabolic acidosis...cycle continues until the acidic conditions completely stop cellular functions (?) and you die.
 
It's been a while for me as well, but I believe the lack of NAD+ causes red blood cells to prematurely die due to inability to protect themselves from reactive oxygen species. This leads to anemia, and therefore, hypoxemia which worsens hypoxia and metabolic acidosis...cycle continues until the acidic conditions completely stop cellular functions (?) and you die.
NAD+ is regenerated by fermentation, that's the point of it. Also, reactive oxygen species aren't going to be generated without oxygen.
 
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