I don't have one but maybe we can start something here:
Keratins are good for carcinomas:
--AE1/AE3
--Pan-cytokeratin
--Cam5.2
--CK7 and CK20 (good for localizing potential sites of origin)
Smooth muscle markers:
--Smooth muscle actin
--Caldesmon
--Desmin
Vascular markers:
--CD34
--CD31
Hematopoietic markers:
--CD3: T-cells
--CD20: B-cells
Proliferation marker:
--Ki-67/MIB-1
Tumor localization markers (the below are transcription factors so they display nuclear localization):
--TTF-1: thyroid or lung tumors
--CDX-2: GI tumors, especially great for ass cancer
--DPC/SMAD4: expression lost in about 50% pancreatic cancers according to the literature; however, empiric practice observation may vary.
Differentiation markers:
--Neuroendocrine: chromogranin, synaptophysin, CD56 might be controversial but works for small cell carcinomas.
--Thyroid: thyroglobulin
--Medullary carcinoma of thyroid: calcitonin
--Mesothelial: D240, calretinin, WT-1
--Prostate: PrSA, PrAP
--Germ cell markers: Oct3/4, SOX2, AFP (also stains some HCCs), PLAP, c-kit
--GISTs: CD34, c-kit, DOG1
--Serous carcinomas of the GYN tract: p53, WT-1
--Renal cell carcinomas: CD10, RCC antigen
--Sex cord stromal tumors of the ovary: inhibin
--Adrenal cortical tumors: inhibin
