Imm qn

[bhuvi]

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2yr boy has had repeated otitis media and pneumonia.serum IgM AND IgG are 25 and 120mg/dl respectively.he has low levels of NADPH oxidase and +ve nitroblue tetrazolium test,whats the diagnosis?
a CGD
b digeorges
c SCID
D w-aldrich syndrome
e x linked agammaglobulinemia

pls explain...thanks

 

[BlackNDecker]

2yr boy has had repeated otitis media and pneumonia.serum IgM AND IgG are 25 and 120mg/dl respectively.he has low levels of NADPH oxidase and +ve nitroblue tetrazolium test,whats the diagnosis?
a CGD
b digeorges
c SCID
D w-aldrich syndrome
e x linked agammaglobulinemia

pls explain...thanks

The answer is D. A positive NBT dye test indicates the patient does not have CGD regardless of the low NADPH oxidase levels(cross out A). He has immunoglobulin(cross out B, C, and D).