inpatient insulin management

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obiwan

Attending Physician
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i've always been confused about this topic... particularly what is the difference between sliding scale and correction scale (at my hospital there are 2 seperate forms for these 2 insulin protocols)

also is there anything else that i need to keep in mind when dealing with a patient's sugars and insulin on the wards?

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i've always been confused about this topic... particularly what is the difference between sliding scale and correction scale (at my hospital there are 2 seperate forms for these 2 insulin protocols)

also is there anything else that i need to keep in mind when dealing with a patient's sugars and insulin on the wards?

I could be WRONG:
RISS- no basal given, just boluses to correct sugar qX hours.
Correction Scale- basal given + correction boluses with first bite.
 
i've always been confused about this topic... particularly what is the difference between sliding scale and correction scale (at my hospital there are 2 seperate forms for these 2 insulin protocols)

also is there anything else that i need to keep in mind when dealing with a patient's sugars and insulin on the wards?

Use a drip in the Unit.

For DKA just follow the algorithm found in pocket medicine. Remember initial bolus dose the rate is 0.1 Units per KG, until the GAP closes, sugars can remain high. Check K often. To reiterate . . . just follow the algorithm.

Sliding scale is probably sort of an insulin only sugar treatment algorithm similar to what they use for the drips only in sub-q form. And the correction scale is what the nurses give to patient already on medications for anything over and above.

After 24 hours of sub-q sliding scale insulin, you should know pretty well how much they will need in 24 hours by adding it up, let's 20 Units in 24 hours. I like to take that number and cut in half (10) and give that as long acting insulin at bedtime (glargine or glitiamer usually, whatever us formulary at your institution . . . OR if money for meds is a problem you can cut your half number in half and give as NPH AM and PM [5 and 5]), and the other half gets given as short acting aspart or regular with meals in three divided doses, ie from out current example 3 Units regular or aspart with breakfast, lunch, and dinner. The 6 am blood sugar will tell you if you need to adjust your evening glargine/glitaimer (or alternative the afternoon NPH, and the afternoon blood sugar will tell you how to adjust the morning NPH if that's th regimine you are using)

Now, you need to hold short acting insulins for NPO status. You're not supposed to need to stop a long acting insulin like glargine or glitiamer for NPO status because these are supposed to control basal sugar metabolism, BUT you'll see people either stopping them altogether or cutting them in half for NPO status.

Think of sulfonylureas like insulins with regard to dosing and the timing of blood sugars - these medications CAN give you hypoglycemia (some are better for liver or kidney disease, so if you have a liver or kidney patient just double check)

Metformin is great first line for newly diagnosed DM2's especially if HgbA1c is <8. Metformin will not give you hypoglycemia (though you will run into at least one attending who will sear they've seen it). Hold these for IV contrast procedures - even though in it's current incarnation metabolic acidosis is almost unheard of, we all do it. No metformin in chronic kidney guys as a rule, but some will tolerate fine (use will probably be attending specific in this group)

In the even of glucose (or sulfonylureal) overdose that will not respond to D50, use a glucagon drip. In these patients giving more glucose only stimulates further intrinsic insulin response. Do not panic, use the glucagon with D50.
 
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Some good information has already been posted and I'll just provide a few points from an endocrine perspective.

1. "Correction scale" is an attempt to move away from the "sliding scale" terminology. Sliding scale-only regimens have been shown to be ineffective (at best) and dangerous (at worst). Using as a temporary tool to determine insulin needs (as JDH suggested) - is one of the only valid uses. Or it can be used in a really mild diabetic. However, it can be hard to get a good sense of insulin needs by just sliding scale alone - so just be aware of that (ie: if someone is on a low dose scale of 1:50 > 150mg/dL, they may be in the 300-400s and only be getting a pitifully small amt of insulin & so their total daily insulin amount will grossly underestimate true needs). Weight-based dosing may be more accurate - or at least get you closer.

2. Remember that there are 3 insulin components to consider when thinking about a diabetic (either type 1 or 2):
-Basal: insulin needed to "exist"
-Meal: insulin needed to cover meals
-"Correction": insulin needed to fix high sugars because life is variable and we don't always calculate the basal and meal doses correctly.

3. You should think about these 3 components and how they are "covered" in each diabetic. Eg:
-your relatively healthy type 2 diabetic in for back pain: basal covered by own pancreas & helped along with a TZD or metformin, meal covered by glipizide, and just needs correction due to pain/stress induced worsening of hyperglycemia
-your type 1 diabetic in for cellulitis: needs basal insulin, meal insulin, and correction
-your type 2 diabetic previously on max oral agents with pre-hosp a1c of 12% now s/p cath: would stop all orals and change to all insulin, etc etc etc
 
1) Oral agents often avoided since easier to titrate insulin as inpatient and also want to avoid drugs like metformin before contrast studies

2) Most common (and easy to titrate) insulin regimen in inpatients is a 4 shot regimen
Options are (a) Lantus (basal at bedtime) + humalog/novolog (with meals) OR NPH (basal at bedtime) + regular (with meals)

3) Calculating daily insulin requirement: ~0.3-0.5 units/kg a day --> usually add 0.1 units/kg for each of the following: HBA1c>7, each oral agent. Usually subtract 0.1 units/kg for each of the following: Chronic kidney disease, Elderly. This calculation provides a reasonable starting point but know that some patients may need up to 1 unit/kg insulin.
So sample daily requirement in 80 yo 70 Kg man with HbA1c 8.4 on metformin and glipizide with baseline creatinine 2.0 is as follows:
Daily requirement = 0.5 + 0.3 (HbA1c>7, each oral agent) - 0.2 (age, CKD) = 0.6 units/kg = 0.6 X 70 kg = 42 units of insulin

4) Insulin dosing after calculating daily requirement:
- NPH and regular: divide 42 units into 4 equal doses = 42/4 = about 10 units insulin --> Regimen is 10 units NPH bedtime, 10 units Reg with meals
- Lantus and Log: 50% is Lantus, remaining is equally divided into 3 doses of Log = 24 units Lantus at bedtime and 8 units Log with meals

5) Calculating sliding scale (correction scale OR supplemental scale) = 5% of total daily requirement = 0.05 X 42 = 2. So sliding scale (short acting insulin) with meals is 150-200 = 2 units, 200-250 4 units, etc. This is intended primarily as a supplement to the scheduled dose of insulin.

6) NPO prior to procedure: Give full dose Lantus. If patient is on NPH then only give half dose. Don't give log (ultra short acting) while NPO

7) Prolonged NPO status: Give 4 shots of regular every 6 hours

8) DKA: use an IV regular insulin infusion
 
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i've always been confused about this topic... particularly what is the difference between sliding scale and correction scale (at my hospital there are 2 seperate forms for these 2 insulin protocols)

also is there anything else that i need to keep in mind when dealing with a patient's sugars and insulin on the wards?

Just consult Endo.

Wait a minute...this isn't the Ortho forum...how did I get in here? Helllpppp!!!

All of the above advice is good. If all you can remember is "basal:bolus = 50:50" and some simple reasoning about how and why people need insulin, you'll pick up the rest along the way.
 
Bumping old thread. question about inpatient diabetes insulin dosing.

So the way I learned was weight in kg / 2 = TDD
50% of TDD is basal lantus, 50% split into 3 is lispro before meals.
Add sliding scale as correction.

My question is what comes next regarding adjust basal and lispro based on sliding scale. I learned this but.. forgot and can not find it anywhere anymore. I was taught its something like add up the insulin sliding scale, and somehow split a portion of it into Basal, and each of the short acting lispro doses.. Can someone help me out with this. Thanks
 
the sliding scale total is added to TDD the next day and you start all over the 50 50 stuff. But if your patient is using NPH or NPH mixed with regular insulin then it's a whole different calculation.
 
Bumping old thread. question about inpatient diabetes insulin dosing.

So the way I learned was weight in kg / 2 = TDD
50% of TDD is basal lantus, 50% split into 3 is lispro before meals.
Add sliding scale as correction.

My question is what comes next regarding adjust basal and lispro based on sliding scale. I learned this but.. forgot and can not find it anywhere anymore. I was taught its something like add up the insulin sliding scale, and somehow split a portion of it into Basal, and each of the short acting lispro doses.. Can someone help me out with this. Thanks

Add up the SS doses and add them on to your TDD. The distribution between basal and qAC is going to depend on what the pt's accuchecks are looking like - e.g. not going to tack half onto basal if their accuchecks are prebreakfast 120 / prelunch 250 / predinner 230 / qhs 290. Before adjusting, should look at accuchecks and talk to pt to see when they're getting their insulin relative to a meal, what they're eating, if they're snacking between meals, etc. If their spiking prebreakfast, should have some suspicion for underdosing or overdosing basal and might consider getting an early am accucheck before adjusting. Obviously I'm not writing orders yet, but this is how I've been taught
 
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