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- Attending Physician
That is a very House-like case 🙂
This was fun. Do more!
Doc Samson IS "House".
That is a very House-like case 🙂
This was fun. Do more!
OK, so first off, you guys rock. If the med students (and some of the residents) I get to deal with every day were 1/2 as enthusiastic as you guys about cases like this, my job would be much easier.
Second, I'm off to Tucson for the APM meeting tomorrow (anyone else going, BTW?), and don't want to leave you all hanging for 5 days until I get back, so here's the gist:
I, also, got hung up on the methadone as an etiology. That one article in the literature (that turned out to be about rhesus monkeys drinking methadone all day long) was something of a red herring.
Next (with the MRI in hand) I went to the heavy metals, with no joy (kinda cool though how this discussion followed my work-up).
As always, "never worry alone" so got some supervision... after digging through his files, the boss pulled out an article on Acquired Non-Wilsonian Hepatocerebral Degeneration. Essentially portosystemic shunting due to hepatic failure leads to exposure of the basal ganglia to all kinds of schmutz (manganese is thought to be a leading contributor), but serum levels of the heavy metals remain wnl. Clinically, it's a dead ringer for Wilson's disease, and has classic MRI findings IDENTICAL to the ones seen in this patient (seriously the scan in the article looked like it was lifted out of his chart). It resolves with liver transplant, which is what this pt is waiting for.
I LOVE my job.
Now, go forth and read.
👍 but without the Vicodin addiction!😀
OK Doc
Could this be confused with any other movement disorder such as Parkinson's?
If the patient past any possible withdrawal phase?
Other meds can cause TD such as Reglan.
OK, so first off, you guys rock. If the med students (and some of the residents) I get to deal with every day were 1/2 as enthusiastic as you guys about cases like this, my job would be much easier.
Second, I'm off to Tucson for the APM meeting tomorrow (anyone else going, BTW?), and don't want to leave you all hanging for 5 days until I get back, so here's the gist:
I, also, got hung up on the methadone as an etiology. That one article in the literature (that turned out to be about rhesus monkeys drinking methadone all day long) was something of a red herring.
Next (with the MRI in hand) I went to the heavy metals, with no joy (kinda cool though how this discussion followed my work-up).
As always, "never worry alone" so got some supervision... after digging through his files, the boss pulled out an article on Acquired Non-Wilsonian Hepatocerebral Degeneration. Essentially portosystemic shunting due to hepatic failure leads to exposure of the basal ganglia to all kinds of schmutz (manganese is thought to be a leading contributor), but serum levels of the heavy metals remain wnl. Clinically, it's a dead ringer for Wilson's disease, and has classic MRI findings IDENTICAL to the ones seen in this patient (seriously the scan in the article looked like it was lifted out of his chart). It resolves with liver transplant, which is what this pt is waiting for.
I LOVE my job.
Now, go forth and read.
One last question...did you get a fasting schmutz level?