Don't start with..."On a bright shining morning on July 10th, 1985 I was born."
Start with college. Give the gist of yourself - major, jobs, activities, etc. The more relaxed you are the more conversational the interview can become so don't force some monologue that would make a monkey fall asleep. Go with the flow and just talk about yourself! I can't believe people have a hard time with it (then again, I might just be egotistical and vain which makes it easy for me 🙂 )
But in all seriousness, I basically had an idea of some topics to mention. Make sure its not too rigid. Its awesome if interviewers stop you and ask you to elaborate. Seriously, almost all of my interviews never got past that question, everything led into everything else and we basically ended up touching on everything the interviewer would have asked anyway - made it super conversational and comfy.
What I wrote down for myself was this (remember I'm not memorizing this, just keeping points in mind).
I'm 22 years old, I graduated in May from UC Berkeley with a degree in Molecular and Cell Biology and an emphasis in Immunology. I am currently working full-time with the Fire Prevention Division at the office on campus where I worked my Junior and Senior year. I worked there as an office assistant for two years and when I graduated the Fire Marshal asked if I would like to stay on to complete a project for them. When Fire fighters respond to buildings they often have maps of the building to know what buildings nearby are threatened and where all the fire suppression equipment in the building is. So I spent 3 months learning AutoCAD for them and am now redoing all 200 buildings on campus. I am also currently teaching an MCAT Biology course for Princeton review – which I like a lot because it keeps the material fresh in my mind while letting me work on how I go about explaining complex material to someone who doesn't understand it.
I also took up a quarter-time Americorps position at the clinic where I have volunteered for 3 years. I have been a medical assistant in the free clinic since my sophomore year and recently started doing follow-up, outreach, and preparation during the daytime as well as my usual job of being a medical assistant in the evening.
I worked part-time all four years of college, and paid my own way through. I worked as a cashier in a café my freshman year which was fun because I got to meet a lot of new people and got a lot of practice in Spanish since so many employees were Hispanic and didn't speak English.
My sophomore year I worked as a tutor and mentor with a bunch of middle school students. That was a lot of fun. They were really cute and a good challenge to work with.
(basically I would start with most recent stuff and go all the way back to major activities at the beginning of college, if you ever get that far - I never did). I don't know if this is a good response, but it worked well for me.
I would say anythign that can make the interview nice and conversational for you is a good answer for you.