Is hemolysis risk factor for gout?

[Saman49]

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Since RBC don't have nucleus why hemolysis is a risk factor for gout?


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[CatFactorial]

hemolysis can cause hyperuricemia, a risk factor for gout.

 

[Saman49]

MTB2 pg 311:
Hemolysis will not cause hyperuricemia because RBCs have no nuclei. #confused


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[HelpPleaseMD]

MTB2 pg 311:
Hemolysis will not cause hyperuricemia because RBCs have no nuclei. #confused


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what about the destruction of the nucleated retriculoytes ?

 

[mercaptovizadeh]

Hemolysis will drive increased cell turnover (reticulocyte response), which means there will be augmented conversion of purines to uric acid via xanthine and hypoxanthine.

 

[HelpPleaseMD]

Hemolysis will drive increased cell turnover (reticulocyte response), which means there will be augmented conversion of purines to uric acid via xanthine and hypoxanthine.

what i meant. just not as sophisticated 🙂