Saman49

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Jan 24, 2012
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Since RBC don't have nucleus why hemolysis is a risk factor for gout?


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Saman49

Saman49

5+ Year Member
Jan 24, 2012
38
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Post Doc
MTB2 pg 311:
Hemolysis will not cause hyperuricemia because RBCs have no nuclei. #confused


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mercaptovizadeh

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Oct 16, 2004
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Hemolysis will drive increased cell turnover (reticulocyte response), which means there will be augmented conversion of purines to uric acid via xanthine and hypoxanthine.
 
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