Is Hormesis a Thing?

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A double stranded break is probably the single most stressful cellular event. Many cellular stressors especially dna damage (heat, O2 depletion, starvation etc) ultimately activate/involve Sirtuins in eukaryotes (lots of pubs ), and hormesis occurs from a variety of these stressors. sirtuins can make things live longer. If it doesnt kill you...

NEJM - Error

So yes, hormesis is very plausible.

https://www.sciencedirect.com/science/article/pii/S1525730414002277
 
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