Is it possible for gluconeogenesis take place in the mitochondria?
(I know it can take place in the cytoplasm, but what about in the mitochondria?)
(I know it can take place in the cytoplasm, but what about in the mitochondria?)
Is it possible for gluconeogenesis take place in the mitochondria?
- Thread starter Gauss44
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There are many steps in the pathway, and some of them can take place within the mitochondria - such as the production of oxaloacetate.
However, the final step utilizes glucose-6-phosphatase to go from glucose-6-phosphate ----> glucose + pi
(the opposite of gluco/hexo-kinase)
This enzyme is mainly (minor exceptions such as parts of kidney) in the liver (attached to the ER).
However, the final step utilizes glucose-6-phosphatase to go from glucose-6-phosphate ----> glucose + pi
(the opposite of gluco/hexo-kinase)
This enzyme is mainly (minor exceptions such as parts of kidney) in the liver (attached to the ER).
