This could be a really important decision. Your entire career can sometimes depend on it. People make the mistake of not giving themselves time to adjust to college all too often.
Why do you think that an upward grade trend is the most common? Is it because the classes are getting easier? No. It is because you will learn to study more and better than you ever have.
Start yourself off gently for the sake of your GPA. Go easy on yourself while you are adjusting to college life. Why risk it? It is really necessary to take ochem, calc, and physiology all in the same semester in your freshman year? No.
If I could go back in time and change the classes I chose to take freshman year, I WOULD. My GPA would probably be 0.2 - 0.3 points higher.
In the end, this is your decision, but just look at the statistics. Most people get their lowest grades during their freshman year. ITs just a fact. Why fall into the statistics? I am not saying that you should take all easy classes, but take out physio and put in an easier pre-rec like english or something. Just my advice.
Most of all, you will do fine no matter what you chose to do, but you will probably do BETTER if you lighten your load a little.
BEST OF LUCK 🙂
Best,
C