If you are at a state school without an outstanding academic record, I'd say take advantage of honors to boost your credibility. From my experience, the honors program is actually helpful grade-wise. A lot of times, honors courses will curve to a B+ because they assume everyone in the class is smart. The material typically isn't much more difficult so you end up with some easy A's. I have not taken any major honor science classes (gen chem, o chem) because those are extremely rigorous, and the non-honors version still count towards my honors degree because they are tough enough. I did take honors intro-biology though which covered pretty much all of the DAT biology, save some physiology/anatomy stuff. Try to find out how difficult your particular program is, but if its anything like I've seen, its definitely worth it.