It depends on why you want to apply ED. If you are absolutely positive this is school you want to attend, then ED may be the best option. The school knows, if accepted you will be coming in the fall, which I am sure many AdComs view positively. I know that Medical College of Georgia accepts a large number of ED students every year. Some of these students have lower MCAT and GPA than the average regular decision applicant. Each school is unique, so you may want to poke around and look for statistics as to how many students are accepted each year ED. -- Now, the rule for ED is all ED applicants must be notified by 10/1. At this time, if you were rejected, your file will rollover into regular admission at that particular school(don't have to pay to reapply regular decision) and you are released to apply to other programs. 10/1 is later in the process, however, many deadlines are not until November-December for AMCAS. -- My advice: If you are absolutely sure this where you want to attend school, then consider the EDP. If there is any doubt, go ahead and submit your AMCAS early regular decision.