Has anyone seen this medication actually work as an adjunct to an SSRI? I am getting some patient's who have been discharged from the hospital (discharge summary is still missing unfortunately) with a diagnosis of MDD and they are being started on Zoloft & Latuda for some reason. They do not appear to be manic/hypomanic so I'm only assuming its as an adjunct.
I feel very strongly that we should maximize an SSRI prior to using adjuncts. I also do not like using antipsychotics due to side effect potential, so I am planning on tapering these people off of it gradually.
On a related note, regarding its formulation, since it does require to be taken with a meal, can I simply tell a pt who is taking 40 mg tab, to cut it in half for 1 week (20 mg) to discontinue? Or does it lose efficacy if you do it that way? Silly question, but not sure.
Thanks
I feel very strongly that we should maximize an SSRI prior to using adjuncts. I also do not like using antipsychotics due to side effect potential, so I am planning on tapering these people off of it gradually.
On a related note, regarding its formulation, since it does require to be taken with a meal, can I simply tell a pt who is taking 40 mg tab, to cut it in half for 1 week (20 mg) to discontinue? Or does it lose efficacy if you do it that way? Silly question, but not sure.
Thanks