List of HLA associated diseases

[cubbyphan]

A3 - primary hemachromatosis
B27 - ankylosing spndylitis, inflammatory bowel, reiter, psoriatic arthritis
DR2/3 - lupus
DR4 - rhematoid arthritis
etc.

Haven't seen a good list of these anywhere. Anyone know where one is or want to just post others in this thread?

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[darice]

FA has a pretty good list......

 

[PeterGriffin]

A3 - primary hemachromatosis
B27 - ankylosing spndylitis, inflammatory bowel, reiter, psoriatic arthritis
DR2/3 - lupus
DR4 - rhematoid arthritis
etc.

Haven't seen a good list of these anywhere. Anyone know where one is or want to just post others in this thread?

B8 - Graves' disease, celiac sprue
DR2 - MS, hay fever, Goodpasteur's, SLE
DR3 - DM type 1, SLE, Sjögren's
DR4 - DM type 1, RA
DR5 - Pernicious anemia, Hashimoto's thyroiditis

 

[prinz]

HLA DR2: goodpastures, allergy, MS, narcolepsy
HLA DR3: celiac sprue, DM I, SLE
HLA DR4: phemigus vulgaris, RA, DM I, lyme disease
HLA DR5: pernicious anemia, RA

 

[velo]

a few mnemonics....

Shaq's (#34) ass so fat he looks like he should have diabetes (DR3/4). His weight is hard on his knees too, so arthritis (4)

DR2 is MS (two words), Goodpasture's (two organs), SLE (Duran duran, two words, sang hungry like the wolf), and hay fever (about which I don't give two ****s)

B8: you ate some wheat, now the situation is grave

DR7: is steroid sensitive nephrotic syndrome...steroids work you lucky duck (7)

 

[cubbyphan]

FA has a pretty good list......

I thught FAs was pretty incomplete. Didnt have hemachromatosis and I have probably seen that 3-4 times on qbank already.

 

[darice]

True, it doesn't have A3, but I thought the list was pretty complete otherwise (pg. 191).....

 

[velo]

I thught FAs was pretty incomplete. Didnt have hemachromatosis and I have probably seen that 3-4 times on qbank already.

I think that was somewhere else in qbank...but I'm not 100% sure, its in some review book

anyway I've also seen B13 for psoriasis a few times.

 

[TX_Longhorn]

some more...got these from Qbank

DR2 (choice A) is associated with hay fever, allergy, multiple sclerosis, and narcolepsy, systemic lupus erythematosus

DR3 (choice B) is associated with Goodpasture's syndrome, graves disease, celiac sprue, Type 1 diabetes mellitus, and
systemic lupus erythematosus.

DR4 (choice C) is associated with lyme disease, pemphigus vulgaris, rheumatoid arthritis, and Type 1 diabetes mellitus.

DR5 class II antigen intrinsic factor(relative risk 5); DR5 is also associated with juvenile rheumatoid arthritis.

 

[Pox in a box]

The consensus from last year's crew was that memorizing these numbers and letter combinations was futile and the NBME is moving away from requiring rote memorization of HLA types. I didn't see any either when I took Step 1.

 

[DoctorWannaBe]

I think that was somewhere else in qbank...but I'm not 100% sure, its in some review book

anyway I've also seen B13 for psoriasis a few times.

This was a question on Qbank. However, First Aid says that B27 is for psoriasis, while Qbank says B27 is for psoriatic arthritis and B13 is for psoriasis without arthritis. Does anyone know which one is correct?

 

[VincentAdultman]

The consensus from last year's crew was that memorizing these numbers and letter combinations was futile and the NBME is moving away from requiring rote memorization of HLA types. I didn't see any either when I took Step 1.

My Kaplan Immuno/proffesor basically said not to waste your time on the HLA's. The time can be used to learn more highyeild stuff, and if you encounter the rare question on the USMLE, to just take the hit.