loading dose and steady state question

[holydivers]

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Hi, if a drug with a 35 hour half life is taken on day 1 at .5 mg and then .375 on the days after when will a steady state occur, how do you get a ballpark figure, thanks.....

 

[aldol16]

Can't you just make a table and do the calculations? Figure out increments of 35 hours and how much drug is in the body at that time, taking into account the doses added.

 

[holydivers]

im assuming day 4 or 5 would be the steady state, is there a way to find out what day, im a philosophy major this isnt my bag

 

[aldol16]

Why are you assuming? How did you reach that conclusion? Approach this problem systematically.

 

[holydivers]

can you do it like this, calculate how much percent of the drug youll lose by the day, so you lose 50 percent in 35 hours, so in 24 hours youd lose 34 percent?

 

[WanderingGuitarist]

What is steady state? It was not in my kaplan books at all!

 

[aldol16]

What is steady state? It was not in my kaplan books at all!

It's exactly what it sounds like. It's when the concentration reaches a steady state.