I'm with pgg on this one, particularly what he mentioned in post #5.
It's not entirely uncommon to get a false LOR with saline, but I like it better than air. What I tend to do is a slight combination: approx 0.5 ml of air + 2.5-3 ml of saline. The little bit of air adds springiness (for lack of a better word), but when you inject, you'll notice it is usually mainly the saline that gets injected. It's just something else to consider. Doing the combination reduced my rate of false LORs. I don't inject the entire volume of air/saline.
In the obese people, particularly when you are beginning, you are probably more likely to get false LOR with saline because you are still in fat and haven't engaged ligament yet (although you may think you have). Air is probably a little less likely to give you false LOR in these patients.
I agree with pgg about using your spinal needle as an additional test. I find it to be helpful when I am in doubt. Advancing an additonal "mm" when I think I'm in the right spot makes me too nervous, although I know many that do it without a problem. I would rather just use the spinal needle test.
If I'm confident my needle is in the epidural space but having trouble threading the catheter, and the deep breath technqiue mentioned by someone else does not help, I look at how deep my catheter is in the needle. If the tip is out of the needle, which it usually is, you are committed to either inserting it or removing it as a whole and starting over. Slow clockwise rotation of the needle with pressure on the epidural catheter sometimes helps in these situations.
If the catheter has not gone out of the needle, you got 2 obvious possibilities: a) your needle is not in the epidural space, or b) the end of your catheter is clotted/covered with blood/tissue. Usually it's (a).
However, I have seen (b) once. The CRNA struggled to get into the epidural space for a C/S block. When he got good LOR, he couldn't CSF or a pop with the spinal needle, and couldn't thread the catheter. He tried at a different space, and same problem. In order to speed things along I stepped in. As soon as I removed the needle tip, I saw the problem. Although the CRNA had inserted the stylet in the epidural needle before redirecting, it didn't clear the clot of blood at the tip. There was enough opening to give the LOR, but not enough to pass the catheter. Redid with new needle at the same level this past LOR --> smooth CSE.
Hope this helped somewhat.