Is your shop doing this yet? What is the protocol you use?
Of course LOGICALLY low-risk PE can be discharged home. In fact PE is probably a normal part of physiology, and most people in their lives get PEs that are either asymptomatic or with barely any symptoms.
That being said, lawyers will see it different. If anything happens to that PE patient you send home, and you have documented PE, there is nothing that will save you.
....In fact PE is probably a normal part of physiology, and most people in their lives get PEs that are either asymptomatic or with barely any symptoms.
never heard that one. Got any sources?
There was a study that I don't have at my fingertips this moment that showed 25% of people had a clinically significant PE on autopsy, but the PE isn't what killed them.
I tell the young women with chest pain that the lungs filter the clots. I say we can check the d-dimer, it's positive, we CT the chest, and find a subsegmental PE, and, now, you're on anticoagulants, for something that is physiologic. I reassure with a normal EKG, and totally normal vital signs. I tell them, if it gets worse, then we go further. Painting the picture of how ****ty it is to be on anticoagulants is what sells it.
True dat.Mortality for PE hasn't improved much in 30 years despite the new anticoagulant treatments. I would agree that logically every stable patient with good vital signs could be discharged with outpatient follow up. Logic doesn't typically figure into most malpractice cases.
True dat.
But all you have to do is call me, get my name in the chart, document that Mr Jones will follow up with me to discuss anticoagulation and you’re pretty much off the hook.
I get called at 3am for much dumber s*** than that on the regular.At 3AM? I work nights BTW
We discharge hestia negative clots with normal cardiac enzymes and no right heart strain. They do get a visit from social work and get manufacturer 30 day starter packs of riva or apix. No point in keeping these people in the hospital and there’s good data to support that.
But, I do work in Texas, so that allows me to do logical things.
How do you arrange for echos to assess for right heart strain? Maybe I'm wrong, but didn't these studies utilize echos? Right heart strain isn't always identified on a CT. Granted, they usually have high clot burden and maybe you just choose not to apply the rule with high clot burden.
You probably do every day. You just don't diagnose or find them.Yeah, here is who I am not discharging ever: someone with a PE. Heh, good one, guys!
That's what I said!You probably do every day. You just don't diagnose or find them.
PEs are like disk bulges. They're ubiquitous. Some are pathologic, others clearly aren't. And then there's middle ground. It used to be that any PE you could diagnose was clinically significant. Now imaging technology allows us to diagnose PEs that probably are just physiologic.
True dat.
But all you have to do is call me, get my name in the chart, document that Mr Jones will follow up with me to discuss anticoagulation and you’re pretty much off the hook.
Let me point out one other thing here too - in my mind (at least from a medicolegal standpoint), this isn't like sending someone home with a HEART score of 2 in which you have not made a "life-threatening diagnosis", but rather just made an assessment of risk. You are sending someone home with a DIAGNOSED PATHOLOGY which still carries real 30 day mortality. The equivalent to this would be, say, sending someone home with a "low risk NSTEMI"..
To gro2001’s last paragraph (he is correct regarding phone calls btw), if your concern is medicolegal liability, you aren’t better off “not testing” and missing something. You’re better off diagnosing it, practicing evidence based medicine, using the appropriate treatment which is described in the literature, and documenting exactly that.
In residency I sent home plenty of low-risk PE's (when my attending wanted it and their name was on the chart). And now I don't.
I will agree that from a practice standpoint sending them home, if they are agreeable with outpatient management, is probably the right thing to do. But from a medicolegal standpoint? Nah. Look, my first responsibility in life is to take care of my family, which means having stable employment and avoiding the stress of having malpractice suits dropped in my lap as much as possible. Sure maybe I'm not "saving the system money" or "saving the patient money". And in this case I don't really give a d***. You think the system gives a flying crap about you or me? You think your patients give a flying crap about you or me? You think they won't try to empty your wallet if they get the chance? If we ever have a system where I can make reasonable medical decisions without fear of lawsuit I'll change my practice. Until then, no way.
Let me point out one other thing here too - in my mind (at least from a medicolegal standpoint), this isn't like sending someone home with a HEART score of 2 in which you have not made a "life-threatening diagnosis", but rather just made an assessment of risk. You are sending someone home with a DIAGNOSED PATHOLOGY which still carries real 30 day mortality. The equivalent to this would be, say, sending someone home with a "low risk NSTEMI". Look, I get that 30 day mortality for low-risk PE is low and probably the same whether they got admitted or not.... And I'll bet you this is also true for say an NSTEMI with a stable patient with resolved chest pain, reasonably normal EKG, and a trop of say 0.2 that on repeat 3 hours later hasn't increased. But are you discharging that NSTEMI patient with outpatient management and close PCP f/u? Yeah I didn't think so. Some things in our system just aren't defensible, and a patient found dead in their bed from a PE 2 days after you discharged them on Xarelto is one of them.
You do realize that this study you quoted to me only had 35 patients in the PE group right? (71 were DVT only). And you do realize 3 patients were totally lost to follow-up, right? Which means they could have been dead for all your know. Do you think this study is adequately powered to detect mortality in low-risk PE patients, especially considering that this was not one of their outcome measures? (Although you could argue recurrent VTE rate is kind of a surrogate for mortality). Are you going to use a single study where only 35 patients with PE were included to determine mortality risk? This is a huge problem in medicine. We get these studies published and immediately people say LOOK LOOK LOOK! This study says I can do XYZ, it's PROOF!! But they don't take the time to really consider what the study is saying, what it is designed and powered to detect and not detect, what the potential limitations are, whether the results can be reproduced, and what else is in the literature.
This metaanalysis from 2017: (PMID: 28525830) looking at literature from 1950-2016 demonstrates an overall 2.83% 90 day mortality rate in patients with PE treated outpatient. And, take a look at Table 1. There are several studies in which HESTIA, PESI, or sPESI were used for inclusion criteria with mortality (of varying length) being a primary outcome, and in several of these studies (including Aujesky, Zondag, Ozsu, Vali, and Den Exeter) there was in fact mortality with a rate between 0.6-3.2%.
So I've showed you a metaanalysis with several studies which clearly show there is mortality risk including in patients in whom HESTIA, PESI, and sPESI criteria are used (whether they go home or not).
Just to be clear - you can have a moderately suspicious story + a positive troponin and still get a HEART score = 2.
Yes I’m aware. That wasn’t my point.
You sure can. But good luck finding these in the real world. Especially the cohort of "I thought this was low risk chest pain, i ran a heart score, they have a positive troponin, but I don't think its an unstable angina, NSTEMI, PE, myocarditis or other worrisome admission-worthy pathology, I still think its low-risk chest pain and I'm still going to apply HEART and discharge them" patients. I haven't met many of those. Just because a theoretical patient wrecks the decision rule, doesn't make it a useless decision rule. And chart buff.
Personally, I have sent some small PE home. I quote PESI in my MDM. I prescribe a NOAC. But I do this in patients with insurance, with clear understanding of what we are doing, who volunteer they WANT this and not to be admitted overnight which I offer them. They also tend not to have many comorbidities, and an obvious reason for their PE. They are a minority of the PE I see.
If I knew which freaking NOAC they could get for <$800 it would be way easier...
That's what I said!
It appears that the point of my (admittedly snarky) post was missed. I suppose I welcomed that by being snarky.
I work in an academic ED. Arguably, part of my job is to advance the standard of care in accordance with the literature. So, I do consider outpatient PE therapy. But please note that earlier I recommended that this be done with the protection of an institutional protocol & some shared decision making. I also said I do it during the day, with the help of a pharmacist, and that if I don't have "all my ducks in a row", I'll admit the patient.
It's funny that so many of us are arguing about this, because it seems like we mostly agree that; In the right patient, under the right circumstances (including medicolegal considerations), this is a reasonable practice. We also seem to agree that it is often (usually?) hard to meet all the necessary criteria, so in order for this practice to become widespread it will require the efforts of more than just EPs' reading articles.
Of course LOGICALLY low-risk PE can be discharged home. In fact PE is probably a normal part of physiology, and most people in their lives get PEs that are either asymptomatic or with barely any symptoms.
That being said, lawyers will see it different. If anything happens to that PE patient you send home, and you have documented PE, there is nothing that will save you.
No. It's a theory but it makes sense. You probably develop small venous clots all the time in your body which get "trapped" by the lungs before they can cause damage to your brain. I don't think any evidence exists, because you would have to subject normal, asymptomatic patients to radiation to find them, and then to not treat would be considered unethical. We just assume that every sub-segmental PE we find on CT is pathologic.
Yep. Not doing it. Don't care what the hospitalist says. It doesn't pay to be an early adaptor on this one.
One of my attendings in residency was always referencing this as something he had heard from one of his attendings many moons ago in his residency but no one could ever find and documentation. I agree it makes sense that the lungs wash out small clots the body naturally makes.
What's that old saying about advances in medicine? Something like, "You don't want to be the first one to change, but you also don't want to be the last."
It would seem pretty reasonable to infer this claim from the fact that, while the rates of diagnosing have gone up & up & up, the mortality rates have stayed pretty steady.
The best advice I got before going to Ranger School was from a guy who had been a Company Commander at Ripcord in Viet Nam with the 101st. "Be the gray man. Don't stand out for the right or wrong reasons."
I think it's reasonable that our new CT scanners are catching benign PEs, but until that is the wide consensus, I am admitting them.
Right lateral chest pain, left subsegmental PE?What I don’t get is that our patient is coming in with chest pain worrying enough that we get a CTA. How is that ever a benign insignifant PE if the patient is symptomatic?
Welcome to the United States!You guys are nuts. Put them on a DOAC, discharge them, and call it a day. At worst, if our patients can't afford a DOAC, I'll put them on LMWH, start Warfarin, bring them back in the next few days till their Warfarin is therapeutic, and D/C them to their GP for followup care. I've never heard of a patient in the EDs where I work, coming back in arrest as a result of this. To admit a stable patient with PE who doesn't require O2 or have submassive/massive PE is silly.
You guys are nuts. Put them on a DOAC, discharge them, and call it a day. At worst, if our patients can't afford a DOAC, I'll put them on LMWH, start Warfarin, bring them back in the next few days till their Warfarin is therapeutic, and D/C them to their GP for followup care. I've never heard of a patient in the EDs where I work, coming back in arrest as a result of this. To admit a stable patient with PE who doesn't require O2 or have submassive/massive PE is silly.
I would argue that he made a poor non-defensible medical decision NOT to re-scan. We know that Warfarin is a reasonable option for PE but there will still be patients who have worsening clot burden despite that, or who are not ALWAYS in the therapeutic INR range for whatever compliance or dietary reasons... I just had a patient like this yesterday. But that just means that they are a warfarin failure and need to be started on a DOAC or LMWH or whatever else. Especially so if its malignancy related PE. And despite this, there will be patients who need 1.25 or 1.5x that dose of LMWH... Doesnt necessarily mean that they need admission.
You guys are nuts. Put them on a DOAC, discharge them, and call it a day. At worst, if our patients can't afford a DOAC, I'll put them on LMWH, start Warfarin, bring them back in the next few days till their Warfarin is therapeutic, and D/C them to their GP for followup care. I've never heard of a patient in the EDs where I work, coming back in arrest as a result of this. To admit a stable patient with PE who doesn't require O2 or have submassive/massive PE is silly.
I've rescanned these folks. You really really want to know if someone is having more PEs while already being treated.Welcome to America, where the med.mal system is not about good or bad medicine - its about good or bad outcomes and the hot potato. I thought you guys up there just prescribed "don't eat the yellow snow" for your PEs, anyways. (I kid, I kid).
Classmate of mine from residency had this case in his first year out: 30-something female with chest pain and an already diagnosed PE. She's on warfarin already, but comes in because "the pain is worse". What is he to do; re-scan her? No. Start another drug? No. (This was before DOACs were a thing). Supportive care and discharge, which is what any doc with good sense would do.
Gal is dead several days later from.... more PEs.
First year out. First lawsuit.
Settled.
I don't kid.
Don't care. Still not going to be an early adaptor on this.