Lyases

[basophilic]

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1. What are good examples of lyases?
What I have: aldolases, ketolases, citrate synthase, fatty acid synthase

2. From, Kaplan in-chapter question:
how does conversion from ATP to cAMP + PPi involve a lyase? Shouldn't ligase be involved here (the reaction is almost identical to that of DNA ligase as well, except it's done on an ATP molecule)?

 

[EParker37]

1. What are good examples of lyases?
What I have: aldolases, ketolases, citrate synthase, fatty acid synthase

2. From, Kaplan in-chapter question:
how does conversion from ATP to cAMP + PPi involve a lyase? Shouldn't ligase be involved here (the reaction is almost identical to that of DNA ligase as well, except it's done on an ATP molecule)?

A lyase is an enzyme that breaks apart molecules by other means than hydrolysis or oxidation. IE Decarboxylase. You kinda answered your own question in the second part. A ligase "glues" things together. So adenylate cyclase would be involved in that reaction since we are breaking bonds, not forming them.