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So I asked my immunology prof this question and she didn't know- it was too clinical for her knowledge. Any ideas? Or should I ask the medical folks?
We know that typically firm, rubbery or stone-like lymph nodes are related to cancer and that soft, moveable, fluctuant ones are just infection related. BUT what is happening at the cellular level in the lymph node to make them feel this way? I read something about the lymph nodes related to cancer having a necrotic center. And I already know that the fluctuant nodes are related to the number of cells proliferating in the germinal centers and being trapped in there from the efferent valve.
Does anyone have any more details on this or know where I can find out the specifics of this? I'm just curious, that's all.
We know that typically firm, rubbery or stone-like lymph nodes are related to cancer and that soft, moveable, fluctuant ones are just infection related. BUT what is happening at the cellular level in the lymph node to make them feel this way? I read something about the lymph nodes related to cancer having a necrotic center. And I already know that the fluctuant nodes are related to the number of cells proliferating in the germinal centers and being trapped in there from the efferent valve.
Does anyone have any more details on this or know where I can find out the specifics of this? I'm just curious, that's all.
