MAC levels

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refreshingred

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So is this right?

0 - 0.3 MAC pt is awake
0.3 - 0.7 - pt asleep
0.7 - 1.0 - anesthesia
1.0 - 1.3 surgical anesthesia
1.3 - 1.6 intubating MAC

An attending quoted the above to me, but I can't find a similar chart in baby Miller or my Clinical Anesthesia textbook.

Does anybody know where I can find the original lit that supports this, or in other words does anybody know where the above came from?
 
That info might be found in Eger's 'The Pharmacology of Inhaled Anesthetics'. I've been told by different attendings that MACawake is 0.5 and MAC-BAR is 1.3-1.5 (depending on the agent).
 
Its in baby Barash.
 
oh yeah? i had a patient wake-up on me today at 0.6 MAC. no kidding. ortho case. i was running sevo and nitrous and had just turned the vapors off. was letting the guy rebreathe. he was at about 30% nitrous and about 0.5% ET sevo and "BING!" his eyes popped open and he was ready for the tube to be yanked. i pulled it out and the first thing he did was scream in pain. (guess my epidural didn't work.)

funny. i guess patients don't read the textbooks.
 
VolatileAgent said:
oh yeah? i had a patient wake-up on me today at 0.6 MAC. no kidding. ortho case. i was running sevo and nitrous and had just turned the vapors off. was letting the guy rebreathe. he was at about 30% nitrous and about 0.5% ET sevo and "BING!" his eyes popped open and he was ready for the tube to be yanked. i pulled it out and the first thing he did was scream in pain. (guess my epidural didn't work.)

funny. i guess patients don't read the textbooks.

Outlier on the bell curve of MAC levels....
 
VolatileAgent said:
oh yeah? i had a patient wake-up on me today at 0.6 MAC. no kidding. ortho case. i was running sevo and nitrous and had just turned the vapors off. was letting the guy rebreathe. he was at about 30% nitrous and about 0.5% ET sevo and "BING!" his eyes popped open and he was ready for the tube to be yanked. i pulled it out and the first thing he did was scream in pain. (guess my epidural didn't work.)

funny. i guess patients don't read the textbooks.

Reminds me of an ACL I did as a resident under epidural on a Tulane football player who had obviously done his share of partying...propofol 150ug/kg/min finally stopped him from talking. Sats stayed fine with a nasal cannula.
 
VolatileAgent said:
funny. i guess patients don't read the textbooks.

Yep, no concept of MAC whatsoever.

Remember - 50% of rats will respond when you pinch their tail with a hemostat at 1 MAC of anything, and 50% don't. MAC is a concept, not a rule.
 
True-mac is only a guideline-remember the machine calculates the mac-you can get burned just by following mac levels
 
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