Making math model of cryopreservation of skin, whats cooling procedure?

[surftheiop]

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Im making a mathematical model of a heat transfer situation in a biological setting for one of my engineering projects.

Seeing as skin has a mathematically nice geometry (essentially a flat slab) Im thinking about making my model on the cryopreservation process of a skin sample.

I've been looking online trying to find the exact methods used to cool the skin and usually the articles are vague and say something like (cools 1C/min) or something of the such.

I was curious if someone could link me to an article that more explicitly explains the cooling process?

The sort of information I'll need to make the model are

1) The media the skin is in while freezing (is it on a metal sheet, in a glass petri dish, sitting directly in liquid N2, being exposed to really cold air, etc.?)

2) When a paper says it is cooled by 1C/min does that mean the actual interior skin temperature or the temperature of the media surronding the skin?

*Edit - Also I've read about process where skin's water is replaced with glycerol(?), but I'd rather not do calculations on that one because I know more about how water behaves while freezing

 

[sore eye asses]

Im making a mathematical model of a heat transfer situation in a biological setting for one of my engineering projects.

Seeing as skin has a mathematically nice geometry (essentially a flat slab) Im thinking about making my model on the cryopreservation process of a skin sample.

I've been looking online trying to find the exact methods used to cool the skin and usually the articles are vague and say something like (cools 1C/min) or something of the such.

I was curious if someone could link me to an article that more explicitly explains the cooling process?

The sort of information I'll need to make the model are

1) The media the skin is in while freezing (is it on a metal sheet, in a glass petri dish, sitting directly in liquid N2, being exposed to really cold air, etc.?)

2) When a paper says it is cooled by 1C/min does that mean the actual interior skin temperature or the temperature of the media surronding the skin?

*Edit - Also I've read about process where skin's water is replaced with glycerol(?), but I'd rather not do calculations on that one because I know more about how water behaves while freezing

I just read this and my brain turned into a turnip.

I suggest you conduct this experiment on the moon. It's your only chance at success.

p.s. the answer to the question people undoubtedly keep asking you is:

Asperger's syndrome.

 

[surftheiop]

I just read this and my brain turned into a turnip.

I suggest you conduct this experiment on the moon. It's your only chance at success.

p.s. the answer to the question people undoubtedly keep asking you is:

Asperger's syndrome.

Ah, that was helpful.

I found a paper from the 80's that had all the data I needed to make the model, so don't stress too much about bringing me some more nuggets of insight.

 

[sore eye asses]

Ah, that was helpful.

I found a paper from the 80's that had all the data I needed to make the model, so don't stress too much about bringing me some more nuggets of insight.

The 80's was a good decade for skin cooling. I'm sure you're well on your way. G'luck!

 

[Fidicinal]

p.s. the answer to the question people undoubtedly keep asking you is:

Asperger's syndrome.

Damn. You's a dick, Sore eye.

Keep it up.