If a biopsy came back negative I would use agent and sux in these individuals, also I would consider their relatives able to receive triggering agents as well. To label a patient positive by virtue labels their blood relatives as positive as well, thereby limiting the anesthetize their relatives may receive. It also limits job opportunities, such as with the military.
I feel it would be poor practice to allow uncertainty in such an issue, to have the patient just tell future anesthesiologists that they may be susceptible? This is your practice? Why even do we bother to have muscle biopsies then? I feel that succinylcholine is a vital paralytic to be able to give to patients and to potentially take that away from a whole family seems poor practice. Where did you learn this?
I think my point is somehow escaping you.
So I think my patient has MH, and I tell them they need to have the CHCT to confirm this. And oh, by the way, there are only four centers in the US that can do this test, and you have to go there to have it done, because the tissue has to be fresh. The test will cost several thousand dollars for the procedure in the hospital, the pathologist, and the surgeon, and of course you have to pay the travel expenses yourself.
I fully understand and appreciate what the "board answer" is, but I'm not sure you appreciate the time and costs involved to the patient.
Here's the real-world non-academic way of doing things. Our recommendation would be that the patient be tested. Can I force the patient to do that? No. Can I anesthetize the patient safely if there is a possibility that they're MH susceptible? Absolutely, and with ease. Would it be nice to know for sure? Of course. Do I have to know for sure? Of course not. We ask
every patient at their pre-op evaluation if they or anyone in their family have had a problem with anesthesia including high temperatures or MH? And if they say yes, do we cancel their surgery? Of course not. We simply do a non-triggering anesthetic and enjoy the rest of the day.
There are MANY anesthesiologists, CRNA's, and AA's that have sworn off using succinylcholine entirely in their practice for ANY patient due to any number of reasons, and in particular, MH potential. Many outpatient surgery centers don't stock it at all because, if they do, they feel obligated to carry dantrolene at a significant cost.
The military aspect is something I had never heard, so I looked it up. MH is indeed a potentially disqualifying disease process, although from what little I read, it appears that waivers might be possible. The main concern appears to be the potential of an MH susceptible patient in a forward operating area where dantrolene likely is not available. However - I would assume that anyone with a known family history of MH that really wants to enlist in the military would certainly find it worth their while to be tested.