Probably not. After your $800,000 down payment, that would give you a mortgage of $192k a year, not enough left over to even pay your property taxes more likely than not.
Look, 99.99% of houses aren't worth in the multiple millions. The rule of thumb for someone who is actually responsible with their money is that your mortgage should not exceed 28% of your gross take home. That would be (for an income of $300,000) a mortgage of no more than $7,000/month, or a mortgage of ~$1.4million (assuming an interest rate of ~4.5% on a jumbo loan), which would be a house of ~$1.7million with a down payment of $340k.
That is to say, a single physician could fairly simply afford a $1-2million house (depending on their priorities). Above that, you start stretching budgets. $3-3.5mm would be doable but would leave you basically no money for anything else, which makes zero sense to me.But outside of buying a penthouse in NYC or something in the middle of SF, $1-2mm is a perfectly reasonable (if not quite large) budget.
Oh, and I'd be quite surprised if anyone on Twitch is pulling in monthly millions. In fact, I'd be surprised if there's more than a tiny fraction of streamers who even make six figures... versus every single doctor can if they want to. I'll take those odds.