I wanted to go to school in my hometown because I'm very family oriented and love Cincy so that was my main motivation but I can tell you that grads from Cincy's MD/PhD program (which is what I'm doing) now teach at Harvard, Univ of Washington and JHU so
I think that pretty much debunks the "you have to go to a top 10 school". It may give you an slight edge, but I'll let my scholarly ability speak for itself any day.
Sure, if money's no object and you like the area and want to go to a top tier school, by all means, do it. I don't think you should feel compelled to do it thinking it's going to get some great advantage later on because one of the profs at Cincy is an MD/PhD from Harvard. I also know of two big name cardiologists here in Cincy, one from Yale and the other from Hopkins that are in a practice with a Cincy grad (who is the senior partner) and a OSU grad.
Having graduated from Miami University (which has a large percentage of professors that are from Ivy league schools), I can tell you that yes, they must have gotten a good education because they were good in the classroom but I had several profs from state schools that were equally well prepared.
I truly believe that this whole process of applying tends to perhaps bring out the worst in us. Most of us are competetive by nature, and anal and then we get into this app process and it just exacerbates those tendencies. Many of us have spent years of of life calculating every move to give us the best possible advantage and we tend to blow things out of proportion. Even if it would only give us a slight edge, we feel compelled to do it. Don't let where you went to school, define your self worth. Any education is what YOU make of it.
I have had physicians from top 10 programs tell me that, although they appreciate their education, it doesn't really matter and they wish they had not come out of school 160K in debt. Let's face it, that kind of debt will effect your quality of living for a while (and your family's) so you have to be sure that it's really what you want and you are willing to sacrifice for it.