Step I Mitosis & Hyperplasia

[BlondeCookie]

Here's a remedial question. I apologize if you clicked on this and wanted to be enlightened.

Mitosis is cell division & duplication. Hyperplasia is increase in number of cells. So, isn't mitosis a type of hyperplasia? Think about it. I don't know.

 

[mr. roboto]

Here's a remedial question. I apologize if you clicked on this and wanted to be enlightened.

Mitosis is cell division & duplication. Hyperplasia is increase in number of cells. So, isn't mitosis a type of hyperplasia? Think about it. I don't know.

I can see what you're trying to get at but hyperplasia is an adaptive response to some sort of stimulus and it requires mitosis to get there. Basically, mitosis is a means to arrive at hyperplasia, a tool so to speak. I'm not sure how else to explain this b/c it seems pretty cut and dry to me that mitosis isn't a type of hyperplasia.

 

[Rugby MD]

so stem cells undergo mitosis, but often it is because they are replacing cells that die off- so while they are multiplying, the net number of cells really doesn't change.
for example
the basal cell layer of your epidermis- constantly dividing via mitosis. if you just started digging ditches for a living, and you were developing callouses, then you would add cells faster than you slough them off- hyperplasia. if you are just normal, you add and slough at the same rate and therefore its just plain old regeneration.
sound about right?

 

[WhoisJohnGalt]

Here's a remedial question. I apologize if you clicked on this and wanted to be enlightened.

Mitosis is cell division & duplication. Hyperplasia is increase in number of cells. So, isn't mitosis a type of hyperplasia? Think about it. I don't know.

I think the problem is your definition. Hyperplasia isn't just increase in number of cells; it's an increase in number of cells beyond the normal number. So your average regular mitosis doesn't result in hyperplasia, because the cells are just dividing to replace dying cells, keeping the number of cells within the normal range. Hyperplasia is when mitosis goes unchecked for some physiologic or pathophysiologic reason, resulting in a greater than NORMAL number of cells. So as the previous poster said, mitosis has to happen in order for hyperplasia to occur, but mitosis is definitely not a type of hyperplasia.

 

[BlondeCookie]

Hey everybody, thanks for all your help. It's really weird to think of hyperplasia in a way that isn't an abnormal pathology. I liked the examples, especially the one about the callouses. Thanks again! 🙂