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Im itching to hijack this thread, but Im not sure how...
 
Question: What kind of bear is best?
Fact: Bears eat beets. Bears. Beets. Battlestar Galactica.

There are basically two schools of thought on this topic.
 
Oooh - can I be Garnett?


only if you are the most intense of the three, and you bang your head against your monitor at least three times before logging on to SDN.
 
only if you are the most intense of the three, and you bang your head against your monitor at least three times before logging on to SDN.

Even having never met the other two, I think it's a safe bet that I'm the most intense.

And now OPD will make a joke about my wife.....
 
Hey, it is a single-purpose tread with its purpose fulfilled, meaning it is free for anything whatsoever. We don't often get such a chance :laugh:
 
In that case, I think someone should tell us about what is up with using antipsychotics to supplement antidepressants. It seems really wierd, and my one psychiatrist mentor doesn't really like it.

Does anyone have any idea what a plausible mechanism is for this drug combo?
 
In that case, I think someone should tell us about what is up with using antipsychotics to supplement antidepressants. It seems really wierd, and my one psychiatrist mentor doesn't really like it.

Does anyone have any idea what a plausible mechanism is for this drug combo?

The atypicals are very dirty and pretty much hit every receptor, serotonin included.
 
And, if someone have failed several anti-depressants, then there is a chance that they suffer an underlying mood control problem, possibly even bipolar in some form of another.
 
In that case, I think someone should tell us about what is up with using antipsychotics to supplement antidepressants. It seems really wierd, and my one psychiatrist mentor doesn't really like it.

I am really worried for you:scared: Stay away from this mentor:meanie:

It is important to know the mechanism of action but even more important is that the combo works very well for many patients. So, keep using it judiciously.
 
I believe the Seroquel Gnomes could explain this best:

1. Hit receptors
2. ?????
3. Profit!

Unless you're talking about dopamine receptors, in which case it's:

1) Maybe gently brush against the receptor, but definitely don't bind to it or block it in any way
2) ?????
3) Profit

You could of course add:

4) Cause sedation, weight gain, perhaps DM
5) Watch profits diminish in fighting of class-action lawsuit
 
Unless you're talking about dopamine receptors, in which case it's:

1) Maybe gently brush against the receptor, but definitely don't bind to it or block it in any way
2) ?????
3) Profit

You could of course add:

4) Cause sedation, weight gain, perhaps DM
5) Watch profits diminish in fighting of class-action lawsuit

Oooh--and don't forget:

6) Develop XR formulation as hedge against patent expiration, and
7) Pull a Zoloft and start applying for multiple FDA indications for XR product.
8) Profit a whole bunch more.
 
You might try augmenting antidepressants with exogenous estrogens, so says that book with the funny pictures.
 
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