my nbme 11 questions

[abelabbot]

dude w/ weakness diarrhea....hyperpigmentation....hyponatremia and hyperkalemia.....pick which region is affected....


i know its addisons disease so I picked A but i got it wrong

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[acciddropping]

What are the other choices?

 

[abelabbot]

lol the other choices were a b c d...jk it was a label thats the problem..i picked the letter corresponding to the top of the adrenal gland which i assumed was the zona glomerulosa..

 

[acciddropping]

Oh...lol if it's an addison, it includes all 3 layers of cortex (G,F,P) destroyed...I would go with hypocortisolism, and so, it's the middle layer (F layer) should be a correct answer? Pigmentation is due to increased increased ACTH and you get increased ACTH when three is a low Cortisol. Aldosterone from G layer is independent of ACTH.