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Got a couple of us stumped before the boards about nalaxone...
What side effect of opioids doesn't it reverse?
What side effect of opioids doesn't it reverse?
Got a couple of us stumped before the boards about nalaxone...
What side effect of opioids doesn't it reverse?
Got a couple of us stumped before the boards about nalaxone...
What side effect of opioids doesn't it reverse?
Chest wall rigidity and constipation are both mu receptor mediated and naloxone is somewhat nonspecific opiod receptor antagonist. Pupillary constriction has an unknown mechanism or not linked to known opioid receptor so that would be my guess although has anyone seen from clinical experience pupillary constriction being reversed after naloxone?
Chest wall rigidity and constipation are both mu receptor mediated
so whats the mechanism behind chest wall rigidity then. I was thinking of it was mu mediated inhibition of inhibitory neurons but just read that its mechanism is not clearly understood could be dopamine,GABA or mu receptor mediated..u seem pretty sure of the answer...mind sharing. Thanks