the NAPLEX seemed more about knowing just a little bit about everything. if there is a topic you are completely unfamiliar with, focus on that first. questions about HTN, DM, etc. are relatively simple and you will be able to narrow it down. but if you know nothing about transplantation, HIV, chemo, rare disease states like MS... you will find yourself getting more questions about those. know the basics. drugs of choice, major counseling points, most important labs to monitor, acute treatment vs maintenance, brand and generic.