natrecor query

[binujackie]

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Can anyone please tell me how to calculate the bolus administration of IV natrecor ,pt weighs 85kg. 😕

 

[binujackie]

I'm not a pharmacist, not even a pharmacy student. But I play one on TV.
I don't even know what Natrecor is.

But, isn't it just 2 mcg/kg over 60 minutes?
So, from the prepared 250ml infusion bag (6mcg/ml), the volume of bolus is patient weight/3....or 28.35ml over 60min.

Better double check my work. Where's a pharmacist? (I need a Check!)

Hey Vet,
thanks for ur input. I see light now!!! 🙂

 

[binujackie]

Vet? Not me. Soy un perdedor! (I'm a loser)
I'm serious. I'm not a pharmacist, not even a pharmacy student.
And I don't even know what Natrecor is.
Glad I could help, though.

Just kidding.....u r the man!! 👍

 

[bsmith]

I agree that it is 2 mcg/kg, but my sources says to run over 60 seconds (for the bolus) then continue with 1 mcg/kg/min for continuous IV infusion for acutely decompensated heart failure. Is there a 60 min bolus?

Can anyone please tell me how to calculate the bolus administration of IV natrecor ,pt weighs 85kg. 😕

 

[MRBPharmD]

I agree that it is 2 mcg/kg, but my sources says to run over 60 seconds (for the bolus) then continue with 1 mcg/kg/min for continuous IV infusion for acutely decompensated heart failure. Is there a 60 min bolus?

Bolus: 2 mcg/kg IV push over 1 minute
Drip: 0.01 mcg/kg/min

In real life, however, we typically will give 1/2 the bolus, wait 10 minutes while monitoring BP, and then give the rest if all goes well. Often, we give no bolus. Natrecor is frequently used in pts with labile BPs (i.e. low!) and hence the bolus is often omitted. It really is a lame drug, with no benefit on mortality and increasing evidence it does more harm than good. We allow 72 hrs. use here at the hospital and then we pull the plug on it.