Sorry for digging up an old thread, but I took nbme 7 recently and would love an explanation on a few of these:
1) 75 year old woman begins treatment for osteoporosis. 2 weeks later she gets a burning sensation in her chest and throat daily, approximately 2 hours after taking her medications. Which of the following medications is the most likely cause of this burning sensation?
Alendronate, Calcitonin, Raloxifene (wrong), Sodium flouride, Vitamin D
It's Alendronate. These come in green/yellow cardbox boxes and when they take these pills,"by mouth" it irritates the throat. One of them clinical questions -_-
2) A study is conducted to estimate the number of procedures performed by general internal medicine physicians. A questionnaire is mailed to 8000 randomly selected physicians. Of these, 5680 (71%) respond. Which of the following measurements most strongly suggests that the respondents represent a heterogeneous population with respect to the number of different procedures performed?
Mean number of
procedures performed, Standard deviation
a) 4, 0.1
b) 7, 1.8 (wrong)
c) 11, 0.5
d) 13, 5.1 (i am guessing this is correct?)
Yes the stronger variability (mixed population) the greater the SD. I don't know how else to explain it.
3) During a study of intravenous urinary catheters, an investigator sterilizes a plastic catheter by incubation in alcohol. This compound acts by disrupting which of the following structures?
Cell wall, DNA, Membrane, Protein (wrong), RNA
Alcohols will always damage the cell wall. I think someone here its like Polymyxin's Antibiotic.
4) A diagram of a pathway of amino acid biosynthesis is shown. Enzymes are indicated by letters, and intermediates of the pathway are indicated by numbers. Compound 5 most likely regulates which of the following labeled enzymes?
1--A--> 2 ---B--> 3 --C--> 4 --D--> 5
|
E
|
6 --F--> 7
Answer choices: A (correct?), B, C, D (wrong), E, F
I selected (A) it was wrong. I am pretty sure it is (D)
This is as best a representation as i can make of the picture lol
* all the letters are 'above' the arrows, i.e enzymes
**the letter E shows an arrow going down from number 2 --E--> 6