Step I negative feedback T4/T3

[step1april2013]

Does T4 have negative feedback on TRH/TSH. In FA it just says T3 has a negative feedback

 

[Pinkleton]

I believe T4 is converted to T3 by a deiodinase in the anterior pituitary, and that T3 acts as negative feedback on T4's behalf. So T4 indirectly negative feedbacks, not directly

 

[step1april2013]

I believe T4 is converted to T3 by a deiodinase in the anterior pituitary, and that T3 acts as negative feedback on T4's behalf. So T4 indirectly negative feedbacks, not directly

thank you for confirming