Your sister-in-law shouldn't give up hope for a pharmacy school just because her GPA isn't up to par. As mentioned above, if she can get her GPA above 2.75 (3.0 would be better) before applying, then she has a DEFINITE shot. (I will vouch for that from personal experience). That being said, she will probably need to enroll in a masters program for two years. A masters program has a few benefits: 1) it will really test her commitment to pharmacy 2) it will demonstrate to the ADCOMs that she really can achieve academically 3) a masters program usually is smaller and allows for better accountability on the students' part, resulting in better scores. 4) Master degrees are a good asset to have...you can get them in almost any field, but good ones to explore would be a masters in public health or healthcare management. I know some state schools have pretty lenient requirements for masters programs.
About the subject about the PCAT score, a stellar PCAT score can sometimes make up for a poor GPA (again from experience). PCAT scores can be raised through practice and dedication (how else do those prep courses make money) If your sister-in-law is willing to practice for months on end, then she has a shot.
That being said, she will also need very good extracurriculars... it would be a good idea to have her explore internships or volunteer work at a local pharmacy so that she gets a good look at the profession, as well as having something to write down on her future application. The more involved she gets in her extracurriculars, the more she will be able to write and the better letters of recommendation she will be able to get.
And for those of you who say it's impossible to make it happen, I'm living proof that it is possible. There was a point in time (unfortunately, for me), when my GPA was pretty much around those marks (*shudder i remember those days*) But I buckled down, worked hard, and got my GPA up to a 2.65. Normally that wouldn't get most students into pharmacy school, but luckily I had my PCAT score for my saving grace. I'll be a P1 this fall at UMB. So you never know. Nothing is impossible in this world. GPA doesn't determine how well you'll do in pharmacy school nor in your career path. So kindly do not put down or discourage those who are down. Because they're not out of the game until they quit. That's why people reapply again and again, because they're hoping to get in. They could use our support. Thank you =)