Oc reaction ???????????

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joemario

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What happens when unsymmetrical acid anhydride react with an alcohol? Two different esther?????
 
correct.

Reacting an alcohol with an acid anhydride:

36abcc3fd4eb3e451378e846e08d6eb0.png


Bear in mind that you will also get a carboxylic acid with the other 'R' group attached as a product

Additionally, the left product should be the dominant one.

This is because during the reaction, one of the carbons forming a ketone is attacked by the alcohol. The attacked carbon breaks the bond with the central oxygen. Because there is less steric hindrance, the probability of attack should be greater.
 
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