S sfoksn Full Member 15+ Year Member Joined Sep 4, 2006 Messages 761 Reaction score 1 Points 4,626 Dental Student Feb 14, 2010 #1 Advertisement - Members don't see this ad cyclohexane with a CH2CN group treated with H3O+ and heat... it becomes cyclohexane with carboxylic acid group attached. why and how? Thank you.
Advertisement - Members don't see this ad cyclohexane with a CH2CN group treated with H3O+ and heat... it becomes cyclohexane with carboxylic acid group attached. why and how? Thank you.
SaSSyBruin Full Member 10+ Year Member 15+ Year Member Joined Sep 13, 2008 Messages 50 Reaction score 0 Points 4,551 Location Los Angeles Pre-Dental Feb 16, 2010 #2 Looks like Nitrile hydrolysis which leads to Carboxylic acid production... The COOH simply replaces the CN and byproduct is ammonia or ammonium salts (Sn2 Reaction)... Upvote 0 Downvote
Looks like Nitrile hydrolysis which leads to Carboxylic acid production... The COOH simply replaces the CN and byproduct is ammonia or ammonium salts (Sn2 Reaction)...
S sfoksn Full Member 15+ Year Member Joined Sep 4, 2006 Messages 761 Reaction score 1 Points 4,626 Dental Student Feb 16, 2010 #3 I understand that, thank you. I was actually specifically asking why this happens. How are the atoms interacting? Upvote 0 Downvote
I understand that, thank you. I was actually specifically asking why this happens. How are the atoms interacting?
S sfoksn Full Member 15+ Year Member Joined Sep 4, 2006 Messages 761 Reaction score 1 Points 4,626 Dental Student Feb 18, 2010 #4 bump Upvote 0 Downvote
L loveoforganic -Account Deactivated- 10+ Year Member Joined Jan 30, 2009 Messages 4,218 Reaction score 14 Points 4,621 Feb 18, 2010 #5 http://chemistry.boisestate.edu/people/richardbanks/organic/nitrilehydrolysisacidicReview.htm Upvote 0 Downvote