opioid tolerance

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epidural man

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  1. Attending Physician
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I seem to recall (but may be imagining things) reading a nice review about the different rates of opioid tolerance between the different drugs, but I can't find anything now.

Anyone have any references to which opioids cause tolerance the quickest? (Besides remifentanil...duh)

I seem to remember that fentanyl is the quickest, methadone the slowest, morphine somewhere in the middle - but can't find any data.

There are lots of studies on OIH - most of those are on morphine.
 
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