Organic Chem Q

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hannah999

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  1. Pre-Dental
Can someone please explain to me why Glycine
would need two equivalents of base to be completely neutralized.

H2NCH2CO2H + -OH --> H2NCH2COO-

how does the second base work?
 
Last edited:
Sure, it is because a fully protonated glycine would have NH3+ and COOH to neutralize. That would need two OH- to be neutralized.
 
Only when glycine is in acidic pH it will need 2 moles of base to be fully neutralized...

Because when glycine is acidic it is like this:

NH3+CH2COOH

When glycine is basic it is like this:

NH2CH2COO-

And physiological pH (pH=7) it is like this:

NH3+CH2COO-
 
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