PA pg 485: why does increased sympathetic tone cause increase in renin?

[angrygunner]

---

Members do not see this ad.

decreased blood pressure is supposed to cause an increase in renin --> in order to cause systemic rise in blood pressure

if you increase sympathetic tone (beta1) you are increasing blood pressure. why would this increase renin?

 

[Choo]

JG cells have beta receptors that release renin.
That's one of the mechanisms by which beta blockers lower blood pressure.

 

[Snuke]

decreased blood pressure is supposed to cause an increase in renin --> in order to cause systemic rise in blood pressure

if you increase sympathetic tone (beta1) you are increasing blood pressure. why would this increase renin?

Maybe I'm looking at this too simply, but don't you want to increase renin production when you need to increase blood pressure?

It's not the increased blood pressure that increases renin, but norephinephrine itself that will activate the beta-1 receptors on juxtaglomerular cells, causing them to secrete renin.

 

[CaptainSSO]

JG cells have beta receptors that release renin.
That's one of the mechanisms by which beta blockers lower blood pressure.

Specifically it's beta-1 receptors.

 

[CaptainSSO]

decreased blood pressure is supposed to cause an increase in renin --> in order to cause systemic rise in blood pressure

if you increase sympathetic tone (beta1) you are increasing blood pressure. why would this increase renin?

You reversed cause and effect. It's the increased renin that causes the increased BP, not vice versa.