PDC

[Maxxxx]

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I know in aerobic conditions PDC turns pyruvate into Acetyl-CoA, but was oxygen used at PDC step?

 

[dyspareunia]

I know in aerobic conditions PDC turns pyruvate into Acetyl-CoA, but was oxygen used at PDC step?

No, O2 is not a cofactor or substrate in PDH.

 

[Czarcasm]

I know in aerobic conditions PDC turns pyruvate into Acetyl-CoA, but was oxygen used at PDC step?

No. The CO2 that's produced is because Pyruvate undergoes a decarboxylation step to produce a product (which later combines with Vitamin A to produce Acetyl-CoA). Two additional decarboxylation steps occur in Kreb's cycle. Oxygen is only presented at the end of the ETC where it functions in oxidative phosphorlyation and is the final electron acceptor to produce H2O.

 

[dyspareunia]

No. The CO2 that's produced is because Pyruvate undergoes a decarboxylation step to produce a product (which later combines with Vitamin A to produce Acetyl-CoA). Two additional decarboxylation steps occur in Kreb's cycle. Oxygen is only presented at the end of the ETC where it functions in oxidative phosphorlyation and is the final electron acceptor to produce H2O.

I think you mean Coenzyme A, not Vitamin A. The cofactors for PDH are B1, B2, B3, B5, and Lipoic acid.

B1 = thiamine pyrophosphate
B2 = FAD
B3 = NAD
B5 = Pantothenic Acid -> CoA

 

[Czarcasm]

I think you mean Coenzyme A, not Vitamin A. The cofactors for PDH are B1, B2, B3, B5, and Lipoic acid.

B1 = thiamine pyrophosphate
B2 = FAD
B3 = NAD
B5 = Pantothenic Acid -> CoA

Yep, you're right. Thanks for catching that.

 

[Maxxxx]

Thanks a lot, guys!