faisal 2000

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Sep 17, 2012
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hi
could you please explain how do antibodies work in phagocytosis ?

Thanks in advance
 
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faisal 2000

5+ Year Member
Sep 17, 2012
327
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Medical Student
Act as opsonin ..... Macrophages have receptor to the fc region of antibody


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thank you my friend
can you explain why specifically igG increased phagocytosis while another antibodies not doing that
 

ChessMaster3000

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Mar 7, 2010
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thank you my friend
can you explain why specifically igG increased phagocytosis while another antibodies not doing that
it just so happens that IgG serves as an opsonin while the other isotypes do not. It depends on its structures, the details of which are beyond any exam short of an Immunology PhD test.
 

notbobtrustme

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thank you my friend
can you explain why specifically igG increased phagocytosis while another antibodies not doing that
Two reasons. One is that IgG is the high affinity antibody and thus will really coat those particles/organisms good. The second is that macrophages have specific receptors for the constant region of IgG, as was already explained. That's really all there is to it.